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Anti-IGFBP1 Antibody

品牌：Antibodies

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规格：100µg

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Anti-IGFBP1 Antibody

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Name:	Anti-IGFBP1 Antibody See all IGFBP1 primary antibodies
Description:	Goat polyclonal antibody to IGFBP1.
Applications:	ELISA, WB
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human IGFBP1 (C terminal).
Sequence:	RIPGSPEIRGDPNCQ
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 µg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
Post-Translational Modification:	Phosphorylated; probably by casein kinase II. Phosphorylation alters the affinity of the protein for IGFs. In amniotic fluid, the unmodified protein is the most abundant form, while mono-, bi-, tri- and tetraphosphorylated forms are present in decreasing amounts. The phosphorylation state may influence the propensity to proteolysis.
Cellular Location:	Secreted.
Database Links:	Entrez Gene: 3484 Human Omim: 146730 Human SwissProt: P08833 Human Unigene: 642938 Human
Synonyms:	AFBP Antibody Alpha pregnancy associated endometrial globulin Antibody Amniotic fluid binding protein Antibody Binding protein 25 Antibody Binding protein 26 Antibody Binding protein 28 Antibody Growth hormone independent binding protein Antibody hIGFBP 1 Antibody hIGFBP1 Antibody IBP 1 Antibody IBP-1 Antibody IBP1 Antibody IBP1_HUMAN Antibody IGF binding protein 1 Antibody IGF BP25 Antibody IGF-binding protein 1 Antibody IGFBP 1 Antibody IGFBP-1 Antibody IGFBP1 Antibody Insulin like growth factor binding protein 1 Antibody Insulin-like growth factor-binding protein 1 Antibody Placental protein 12 Antibody PP 12 Antibody PP12 Antibody
Information:	Target information shown above is from the UniProt Consortium.