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Anti-ID3 Antibody

品牌：Antibodies

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规格：50µl

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Anti-ID3 Antibody

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Overview

Name:	Anti-ID3 Antibody See all ID3 primary antibodies
Description:	Rabbit polyclonal antibody to ID3.
Applications:	WB, IHC, IF
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human ID3.
Protein Length:	119
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer.
Tissue Specificity:	Expressed abundantly in lung, kidney and adrenal gland, but not in ***** brain.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 3399?Human Entrez Gene: 15903?Mouse Omim: 600277?Human SwissProt: Q02535?Human SwissProt: P41133?Mouse Unigene: 76884?Human Unigene: 110?Mouse
Synonyms:	1R21 Antibody bHLHb25 Antibody Class B basic helix-loop-helix protein 25 Antibody DNA binding protein inhibitor ID 3 Antibody DNA-binding protein inhibitor ID-3 Antibody HEIR 1 Antibody HEIR1 Antibody Helix loop helix protein HEIR 1 Antibody Helix loop helix protein HEIR1 Antibody Helix-loop-helix protein HEIR-1 Antibody HLH642 Antibody ID 3 Antibody ID like protein inhibitor HLH 1R21 Antibody ID like protein inhibitor HLH 462 Antibody ID-like protein inhibitor HLH 1R21 Antibody ID3 Antibody ID3_HUMAN Antibody Inhibitor of DNA binding 3 Antibody Inhibitor of DNA binding 3 dominant negative helix loop helix protein Antibody
Information:	Target information shown above is from the UniProt Consortium.