Anti-Histone H3.1 (Ab-10) Antibody |产品详情|进口试剂采购网

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Anti-Histone H3.1 (Ab-10) Antibody

品牌：Antibodies

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规格：50µl

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Anti-Histone H3.1 (Ab-10) Antibody

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Overview

Name:	Anti-Histone H3.1 (Ab-10) Antibody See all Histone H3.1 primary antibodies
Description:	Rabbit polyclonal antibody to Histone H3.1 (Ab-10)
Specificity:	The antibody detects endogenous level of total Histone H3.1 protein.
Applications:	WB, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Peptide sequence around aa.8~12 (R-K-S-T-G) derived from Human Histone H3.1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration:	1.0mg / ml
Formulation:	Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target

Function:	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Sequence Similarities:	Belongs to the histone H3 family.
Post-Translational Modification:	Acetylation is generally linked to gene activation. Acetylation on Lys-10 (H3K9ac) impairs methylation at Arg-9 (H3R8me2s). Acetylation on Lys-19 (H3K18ac) and Lys-24 (H3K24ac) favors methylation at Arg-18 (H3R17me). Acetylation at Lys-123 (H3K122ac) by EP300/p300 plays a central role in chromatin structure: localizes at the surface of the histone octamer and stimulates transcription, possibly by promoting nucleosome instability.
Cellular Location:	Nucleus. Chromosome.
Database Links:	Entrez Gene: 8350 Human Entrez Gene: 8351 Human Entrez Gene: 8352 Human Entrez Gene: 8353 Human Entrez Gene: 8354 Human Entrez Gene: 8355 Human Entrez Gene: 8356 Human Entrez Gene: 8357 Human Entrez Gene: 8358 Human Entrez Gene: 8968 Human Entrez Gene: 319148 Mouse Entrez Gene: 319151 Mouse Entrez Gene: 319152 Mouse Entrez Gene: 319153 Mouse Entrez Gene: 360198 Mouse Entrez Gene: 97908 Mouse Omim: 602810 Human Omim: 602811 Human Omim: 602812 Human Omim: 602813 Human Omim: 602814 Human Omim: 602815 Human Omim: 602816 Human Omim: 602817 Human Omim: 602818 Human Omim: 602819 Human SwissProt: P68431 Human SwissProt: P68433 Mouse Unigene: 132854 Human Unigene: 247813 Human Unigene: 247814 Human Unigene: 248176 Human Unigene: 443021 Human Unigene: 484990 Human Unigene: 532144 Human Unigene: 533292 Human Unigene: 546315 Human Unigene: 586261 Human Unigene: 591778 Human Unigene: 626666 Human Unigene: 221301 Mouse Unigene: 261657 Mouse Unigene: 377874 Mouse Unigene: 390558 Mouse Unigene: 397328 Mouse
Synonyms:	H3 histone family, member A Antibody H3 histone family, member B Antibody H3 histone family, member C Antibody H3 histone family, member D Antibody H3 histone family, member E Antibody H3 histone family, member F Antibody H3 histone family, member G Antibody H3 histone family, member H Antibody H3 histone family, member I Antibody H3 histone family, member J Antibody H3 histone family, member K Antibody H3 histone family, member L Antibody H3.1 Antibody H3.f Antibody H3/A Antibody H3/c Antibody H3/d Antibody H3/f Antibody H3/h Antibody H3/i Antibody H3/j Antibody H3/k Antibody H3/l Antibody H31_HUMAN Antibody H3F1K Antibody H3FA Antibody H3FB Antibody H3FC Antibody H3FD Antibody H3FF Antibody H3FH Antibody H3FI Antibody H3FJ Antibody H3FK Antibody H3FL Antibody HIST1 cluster H3A Antibody HIST1 cluster H3B Antibody HIST1 cluster H3C Antibody HIST1 cluster H3D Antibody HIST1 cluster H3E Antibody HIST1 cluster H3F Antibody HIST1 cluster H3G Antibody HIST1 cluster H3I Antibody HIST1 cluster H3J Antibody HIST1H3A Antibody HIST1H3B Antibody HIST1H3C Antibody HIST1H3E Antibody HIST1H3F Antibody HIST1H3G Antibody HIST1H3H Antibody HIST1H3I Antibody HIST1H3J Antibody histone 1, H3a Antibody histone 1, H3b Antibody Histone 1, H3c Antibody Histone 1, H3e Antibody histone 1, H3f Antibody histone 1, H3g Antibody histone 1, H3h Antibody histone 1, H3i Antibody histone 1, H3j Antibody histone cluster 1, H3a Antibody histone cluster 1, H3b Antibody Histone cluster 1, H3c Antibody Histone cluster 1, H3e Antibody histone cluster 1, H3g Antibody histone cluster 1, H3h Antibody histone cluster 1, H3i Antibody histone cluster 1, H3j Antibody Histone gene cluster 1 H3A Antibody Histone gene cluster 1 H3B Antibody Histone gene cluster 1 H3E Antibody Histone gene cluster 1 H3F Antibody Histone gene cluster 1 H3G Antibody Histone gene cluster 1, H3 Antibody Histone gene cluster 1, H3C Antibody Histone gene cluster 1, H3D Antibody Histone gene cluster 1, H3I Antibody Histone gene cluster 1, H3IH Antibody Histone H3.1 Antibody Histone H3/a Antibody Histone H3/b Antibody Histone H3/c Antibody Histone H3/d Antibody Histone H3/f Antibody Histone H3/h Antibody Histone H3/i Antibody Histone H3/j Antibody Histone H3/k Antibody Histone H3/l Antibody
Information:	Target information shown above is from the UniProt Consortium.