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Anti-FOXC2 Antibody

品牌：Antibodies

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规格：100µg

货期：

应用：

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Anti-FOXC2 Antibody

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Overview

Name:	Anti-FOXC2 Antibody See all FOXC2 primary antibodies
Description:	Goat polyclonal antibody to FOXC2.
Applications:	ELISA, WB
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human FOXC2 (C terminal).
Sequence:	RHAAPYSYDCTKY
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 µg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Transcriptional activator. Might be involved in the formation of special mesenchymal tissues.
Involvement in Disease:	Lymphedema-distichiasis: A disorder characterized by primary limb lymphedema associated with distichiasis (double rows of eyelashes, with extra eyelashes growing from the Meibomian gland orifices). Swelling of the extremities, due to altered lymphatic flow, usually appears in late childhood or puberty. Most affected individuals have ocular findings including corneal irritation, recurrent conjunctivitis, and photophobia. Drooping of the upper eyelid (ptosis) is a variable feature of the lymphedema-distichiasis syndrome, occurring in about 30% of patients.
Post-Translational Modification:	Phosphorylation regulates FOXC2 transcriptional activity by promoting its recruitment to chromatin.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 2303 Human Omim: 602402 Human SwissProt: Q99958 Human Unigene: 436448 Human
Synonyms:	Drosphilia Forkhead Homolog Like 14 Antibody FKHL 14 Antibody FKHL14 Antibody Forkhead Box C2 Antibody Forkhead box protein C2 Antibody Forkhead related protein FKHL14 Antibody Forkhead-related protein FKHL14 Antibody FOX C2 Antibody FOXC2 Antibody FOXC2_HUMAN Antibody LD Antibody Mesenchyme fork head protein 1 Antibody Mesenchyme Forkhead 1 Antibody MFH 1 Antibody MFH 1 protein Antibody MFH-1 protein Antibody MFH1 Antibody Transcription factor FKH 14 Antibody Transcription factor FKH-14 Antibody
Information:	Target information shown above is from the UniProt Consortium.