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Anti-Bmi1 Antibody

品牌：Antibodies

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规格：50µl

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Anti-Bmi1 Antibody

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Overview

Name:	Anti-Bmi1 Antibody See all Bmi1 primary antibodies
Description:	Mouse monoclonal antibody to Bmi1
Specificity:	This antibody detects endogenous levels of Bmi1 and does not cross-react with related proteins.
Applications:	WB, ICC, IHC, FC
Reactivity:	Human, Mouse, Rat
Immunogen:	This antibody is produced by immunizing mice with a recombinant protein corresponding to a region of Bmi1.
Host:	Mouse
Clonality:	Monoclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 37 kDa
Purity:	Protein A affinity purified
Product Form:	Mouse IgG2a. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Target

Function:	Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Post-Translational Modification:	Monoubiquitinated (By similarity). May be polyubiquitinated; which does not lead to proteasomal degradation.
Cellular Location:	Nucleus. Cytoplasm.
Database Links:	Entrez Gene: 100532731?Human Entrez Gene: 648?Human Entrez Gene: 12151?Mouse Entrez Gene: 307151?Rat Omim: 164831?Human SwissProt: P35226?Human SwissProt: P25916?Mouse Unigene: 380403?Human Unigene: 289584?Mouse
Synonyms:	B lymphoma Mo MLV insertion region (mouse) Antibody B lymphoma Mo MLV insertion region 1 homolog Antibody Bmi 1 Antibody Bmi1 Antibody BMI1 polycomb ring finger oncogene Antibody BMI1_HUMAN Antibody Flvi 2/bmi 1 Antibody FLVI2/BMI1 Antibody MGC12685 Antibody Murine leukemia viral (bmi 1) oncogene homolog Antibody Oncogene BMI 1 Antibody PCGF 4 Antibody PCGF4 Antibody Polycomb complex protein BMI 1 Antibody Polycomb complex protein BMI-1 Antibody Polycomb group protein Bmi1 Antibody Polycomb group ring finger 4 Antibody Polycomb group RING finger protein 4 Antibody RING finger protein 51 Antibody RNF 51 Antibody RNF51 Antibody
Information:	Target information shown above is from the UniProt Consortium.