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Anti-SF3B3 Antibody

品牌：Antibodies

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规格：50µl

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Anti-SF3B3 Antibody

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Name:	Anti-SF3B3 Antibody See all SF3B3 primary antibodies
Description:	Rabbit polyclonal antibody to SF3B3.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human SF3B3.
Protein Length:	1217
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Sequence Similarities:	Belongs to the RSE1 family.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 23450?Human Entrez Gene: 101943?Mouse Entrez Gene: 292019?Rat Omim: 605592?Human SwissProt: Q15393?Human SwissProt: Q921M3?Mouse Unigene: 514435?Human Unigene: 236123?Mouse
Synonyms:	KIAA0017 Antibody Pre mRNA splicing factor SF3b 130 kDa subunit Antibody Pre-mRNA-splicing factor SF3b 130 kDa subunit Antibody RSE1 Antibody SAP 130 Antibody SAP130 Antibody SF3b130 Antibody SF3B3 Antibody SF3B3_HUMAN Antibody Spliceosome associated protein 130 Antibody Spliceosome-associated protein 130 Antibody Splicing factor 3B subunit 3 Antibody Splicing factor 3b subunit 3 130kD Antibody STAF130 Antibody
Information:	Target information shown above is from the UniProt Consortium.