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Anti-SEPT7 Antibody

品牌：Antibodies

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规格：50µl

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Anti-SEPT7 Antibody

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Overview

Name:	Anti-SEPT7 Antibody See all SEPT7 primary antibodies
Description:	Rabbit polyclonal antibody to SEPT7.
Applications:	WB, IHC, IF
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human SEPT7.
Protein Length:	437 (436)
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830).
Tissue Specificity:	Widely expressed.
Sequence Similarities:	Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
Cellular Location:	Cytoplasm. Chromosome > Centromere > Kinetochore. Cytoplasm > Cytoskeleton > Spindle. Cleavage furrow. Midbody. Cytoplasm > Cytoskeleton > Cilium axoneme. Cell projection > Cilium > Flagellum. Distributed throughout the cytoplasm in prometaphase cells. Associated with the spindle during metaphase. Associated with the central spindle and at the cleavage furrow in anaphase cells. Detected at the midbody in telophase. Associated with actin stress fibers (By similarity). Found in the sperm annulus (PubMed:25588830).
Database Links:	Entrez Gene: 989?Human Entrez Gene: 235072?Mouse Entrez Gene: 64551?Rat Omim: 603151?Human SwissProt: Q16181?Human SwissProt: O55131?Mouse SwissProt: Q9WVC0?Rat Unigene: 191346?Human Unigene: 270259?Mouse Unigene: 48701?Rat
Synonyms:	CDC10 Antibody CDC10 protein homolog Antibody CDC3 Antibody Cell division cycle 10 Antibody NBLA02942 Antibody SEPT7 Antibody SEPT7A Antibody SEPT7_HUMAN Antibody Septin 7 Antibody Septin-7 Antibody
Information:	Target information shown above is from the UniProt Consortium.