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Anti-ASF1A Antibody

品牌：Antibodies

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规格：50µl

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Anti-ASF1A Antibody

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Name:	Anti-ASF1A Antibody See all ASF1A primary antibodies
Description:	Rabbit polyclonal antibody to ASF1A
Specificity:	ASF1A polyclonal antibody detects endogenous levels of ASF1A protein.
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant full length Human ASF1A.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 23 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.

Function:	Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
Tissue Specificity:	Ubiquitously expressed.
Sequence Similarities:	Belongs to the ASF1 family.
Post-Translational Modification:	Phosphorylated by TLK1 and TLK2. Highly phosphorylated in S-phase and at lower levels in M-phase. TLK2-mediated phosphorylation at Ser-192 prevents proteasome-dependent degradation.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 25842?Human Entrez Gene: 66403?Mouse Entrez Gene: 294408?Rat Omim: 609189?Human SwissProt: Q9Y294?Human SwissProt: Q9CQE6?Mouse Unigene: 292316?Human Unigene: 272989?Mouse
Synonyms:	Anti silencing function 1A Antibody Anti-silencing function protein 1 homolog A Antibody ASF1 anti silencing function 1 homolog A Antibody ASF1 anti silencing function 1 homolog A (S. cerevisiae) Antibody ASF1A Antibody ASF1A_HUMAN Antibody CCG1 interacting factor A Antibody CCG1-interacting factor A Antibody CGI 98 Antibody CIA Antibody hAsf1 Antibody hAsf1a Antibody hCIA Antibody Histone chaperone ASF1A Antibody HSPC146 Antibody
Information:	Target information shown above is from the UniProt Consortium.