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Anti-DUSP1 Antibody

品牌：Antibodies

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规格：100µg

货期：

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Anti-DUSP1 Antibody

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Name:	Anti-DUSP1 Antibody See all DUSP1 primary antibodies
Description:	Goat polyclonal antibody to DUSP1.
Applications:	ELISA, WB, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human DUSP1 (C terminal).
Sequence:	SYLQSPITTSPSC
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Tissue Specificity:	Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.
Sequence Similarities:	Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Post-Translational Modification:	Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 1843?Human Omim: 600714?Human SwissProt: P28562?Human Unigene: 171695?Human
Synonyms:	CL 100 Antibody CL100 Antibody Dual Specificity Phosphatase 1 Antibody Dual specificity protein phosphatase 1 Antibody Dual specificity protein phosphatase hVH1 Antibody DUS1_HUMAN Antibody DUSP 1 Antibody DUSP1 Antibody HVH1 Antibody MAP kinase phosphatase 1 Antibody Mitogen-activated protein kinase phosphatase 1 Antibody MKP-1 Antibody MKP1 Antibody Protein tyrosine phosphatase CL100 Antibody Protein-tyrosine phosphatase CL100 Antibody PTPN10 Antibody Serine/threonine specific protein phosphatase Antibody VH1 Antibody
Information:	Target information shown above is from the UniProt Consortium.