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Anti-CBR1 Antibody

品牌：Antibodies

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规格：100µg

货期：

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Anti-CBR1 Antibody

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Name:	Anti-CBR1 Antibody See all CBR1 primary antibodies
Description:	Goat polyclonal antibody to CBR1.
Applications:	ELISA, WB, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human CBR1 (C terminal).
Sequence:	C-HGQFVSEKRVEQW
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
Sequence Similarities:	Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Cellular Location:	Cytoplasm.
Database Links:	Entrez Gene: 873?Human Omim: 114830?Human SwissProt: P16152?Human Unigene: 606200?Human Unigene: 88778?Human
Synonyms:	15 hydroxyprostaglandin dehydrogenase [NADP+] Antibody 15-hydroxyprostaglandin dehydrogenase [NADP+] Antibody Carbonyl Reductase 1 Antibody Carbonyl reductase [NADPH] 1 Antibody CBR 1 Antibody CBR1 Antibody CBR1_HUMAN Antibody CRN Antibody NADPH dependent carbonyl reductase 1 Antibody NADPH-dependent carbonyl reductase 1 Antibody Prostaglandin 9 ketoreductase Antibody Prostaglandin 9-ketoreductase Antibody Prostaglandin E(2) 9 reductase Antibody Prostaglandin-E(2) 9-reductase Antibody SDR21C1 Antibody
Information:	Target information shown above is from the UniProt Consortium.