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Anti-NUMB Antibody

品牌：Antibodies

货号：

规格：100µg

货期：

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Anti-NUMB Antibody

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Name:	Anti-NUMB Antibody See all NUMB primary antibodies
Description:	Goat polyclonal antibody to NUMB.
Applications:	ELISA, WB, ICC, IP
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide corresponding to Human NUMB (C terminal).
Sequence:	C-PFSSDLQKTFEIEL
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 µg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage (By similarity).
Post-Translational Modification:	Phosphorylated on Ser-275 and Ser-294 by CaMK1.
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 8650 Human Entrez Gene: 18222 Mouse Entrez Gene: 29419 Rat Omim: 603728 Human SwissProt: P49757 Human SwissProt: Q9QZS3 Mouse SwissProt: Q2LC84 Rat Unigene: 654609 Human Unigene: 714879 Human Unigene: 4390 Mouse Unigene: 102078 Rat
Synonyms:	C14orf41 Antibody c14_5527 Antibody FLJ31314 Antibody h Numb Antibody h-Numb Antibody NUMB Antibody Numb homolog Antibody Numb homolog (Drosophila) Antibody Numb protein homolog Antibody NUMB_HUMAN Antibody Protein numb homolog Antibody Protein S171 Antibody S171 Antibody
Information:	Target information shown above is from the UniProt Consortium.