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Anti-CD54 Antibody

品牌：Antibodies

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规格：100µg

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Anti-CD54 Antibody

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Name:	Anti-CD54 Antibody See all ICAM1 primary antibodies
Description:	Mouse monoclonal (MEM-111) antibody to CD54.
Specificity:	The antibody MEM-111 reacts with CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus). The expression of CD54 is upregulated by activation; it is expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells.
Applications:	FC, WB, IHC-P, ELISA
Reactivity:	Rat, Human, Bovine
Immunogen:	Raji human Burkitt's lymphoma cell line.
Host:	Mouse
Clonality:	Monoclonal
Clone:	MEM-111
Isotype:	IgG2a
Conjugate:	Unconjugated
Purification:	Protein A chromatography.
Concentration:	1 mg/ml
Purity:	> 95% (by SDS-PAGE)
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.4, with 15mM Sodium Azide.
Storage:	Store at 2-8°C.

Function:	ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity).
Sequence Similarities:	Belongs to the immunoglobulin superfamily. ICAM family.
Post-Translational Modification:	Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 3383?Human Entrez Gene: 25464?Rat Omim: 147840?Human SwissProt: P05362?Human SwissProt: Q00238?Rat Unigene: 643447?Human Unigene: 12?Rat
Synonyms:	Antigen identified by monoclonal Antibody BB 2 Antibody BB2 Antibody CD 54 Antibody CD54 Antibody CD54 antigen Antibody CD_antigen=CD54 Antibody Cell surface glycoprotein P3.58 Antibody Human rhinovirus receptor Antibody ICAM 1 Antibody ICAM-1 Antibody ICAM1 Antibody ICAM1_HUMAN Antibody Intercellular adhesion molecule 1 Antibody intercellular adhesion molecule 1 (CD54), human rhinovirus receptor Antibody Major group rhinovirus receptor Antibody MALA 2 Antibody MALA2 Antibody MGC6195 Antibody MyD 10 Antibody MyD10 Antibody P3.58 Antibody Surface antigen of activated B cells Antibody Surface antigen of activated B cells, BB2 Antibody
Information:	Target information shown above is from the UniProt Consortium.