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Anti-STRO-1 Antibody

品牌：Antibodies

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规格：100µg

货期：

应用：

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Anti-STRO-1 Antibody

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Overview

Name:	Anti-STRO-1 Antibody See all STRO-1 primary antibodies
Description:	Mouse monoclonal (STRO-1) antibody to STRO-1.
Specificity:	The mouse monoclonal antibody STRO-1 recognizes the cell surface antigen STRO-1 expressed by bone marrow mesenchymal stromal cells and nucleated erythroid precursors, but not by committed hematopoietic progenitors.
Applications:	FC, ICC
Reactivity:	Human
Immunogen:	Human CD34 positive bone marrow cells.
Host:	Mouse
Clonality:	Monoclonal
Clone:	STRO-1
Isotype:	IgM
Conjugate:	Unconjugated
Purification:	Purified from cell culture supernatant by precipitation and ion exchange chromatography.
Concentration:	1 mg/ml
Purity:	> 95% (by SDS-PAGE)
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 8.0, with 15mM Sodium Azide.
Storage:	Store at 2-8°C.

Target

Introduction:

STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow, identified by monoclonal antibody STRO-1. Approximately 10% of mononuclear cells, greater than 95% of which are nucleated erythroid precursors, are STRO-1 positive, whereas the CFU-GM (colony-forming unit granulocyte-macrophage), BFU-E (erythroid burst) and CFU-Mix (mixed colonies) committed progenitor cells are negative. CFU-F (fibroblast colony-forming cells) are present exclusively in the STRO-1 positive population. When plated under long-term bone marrow culture conditions, STRO-1 positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, osteoblasts, chondrocytes, and fibroblastic elements. In combination with glycophorin A, STRO-1 is a useful marker for identification of mesenchymal stem cells. STRO-1 and CD117 are markers for osteosarcoma cells.

Synonyms:

STRO-1 Antibody

STRO1 Antibody

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