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Anti-CD138 Antibody

品牌：Antibodies

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规格：100µg

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Anti-CD138 Antibody

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Name:	Anti-CD138 Antibody See all CD138 primary antibodies
Description:	Mouse monoclonal (B-A38) antibody to CD138.
Specificity:	The antibody B-A38 recognizes CD138 (syndecan 1), a 65-70 kDa heparan sulfate proteoglycan expressed mainly in the epidermis and plasma cells, but also in growth factor-stimulated lymphocytes.
Applications:	FC, IHC
Reactivity:	Human
Immunogen:	U266 human peripheral blood myeloma cell line.
Host:	Mouse
Clonality:	Monoclonal
Clone:	B-A38
Isotype:	IgG1
Conjugate:	Unconjugated
Purification:	Protein A chromatography.
Concentration:	1 mg/ml
Purity:	> 95% (by SDS-PAGE)
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.4, without Azide (0.2 μm filter sterilised).
Storage:	Store at 2-8°C.

Function:	Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).
Sequence Similarities:	Belongs to the syndecan proteoglycan family.
Post-Translational Modification:	Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.
Cellular Location:	Membrane. Secreted. Secreted > Exosome. Shedding of the ectodomain produces a soluble form.
Database Links:	Entrez Gene: 6382?Human Omim: 186355?Human SwissProt: P18827?Human Unigene: 224607?Human Unigene: 665958?Human
Synonyms:	CD138 Antibody CD138 antigen Antibody CD_antigen Antibody heparan sulfate proteoglycan fibroblast growth factor receptor Antibody SDC Antibody Sdc1 Antibody SDC1_HUMAN Antibody SYND1 Antibody Syndecan Antibody Syndecan 1 Antibody syndecan proteoglycan 1 Antibody Syndecan-1 Antibody
Information:	Target information shown above is from the UniProt Consortium.