Anti-MMP2 Antibody |产品详情|进口试剂采购网

您好，欢迎来到拜力生物网站！请登录注册

我的订单 | 联系我们 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA试剂盒、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口试剂、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于我们

所在位置：首页 > 产品中心 > Antibodies > Antibodies产品

订购信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-MMP2 Antibody

品牌：Antibodies

货号：

规格：50µl

货期：

应用：

咨询客服

立即购买加入购物车

Anti-MMP2 Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-MMP2 Antibody See all MMP2 primary antibodies
Description:	Rabbit polyclonal antibody to MMP2.
Applications:	WB, ICC/IF, IHC
Dilutions:	WB: 1:10,000. IF/ICC and IHC: 1:500-1:1,000.
Reactivity:	Human, Horse, Cow, Porcine, Chicken, Rat, Mouse
Immunogen:	Human C-terminal peptide (aa. 475-490).
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Immunogen affinity purified.
Concentration:	1 mg/ml
Product Form:	Liquid
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-\|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues (By similarity).
Sequence Similarities:	Belongs to the peptidase M10A family.
Post-Translational Modification:	Phosphorylation on multiple sites modulates enzymatic activity. Phosphorylated by PKC in vitro (By similarity).
Cellular Location:	Secreted > Extracellular space > Extracellular matrix. Membrane. Nucleus. Colocalizes with integrin alphaV/beta3 at the membrane surface in angiogenic blood vessels and melanomas. Found in mitochondria, along microfibrils, and in nuclei of cardiomyocytes (By similarity).
Database Links:	Entrez Gene: 386583386583?Chicken Entrez Gene: 282872?Cow Entrez Gene: 4313?Human Entrez Gene: 17390?Mouse Entrez Gene: 397391?Pig Entrez Gene: 81686?Rat Omim: 120360?Human SwissProt: Q90611?Chicken SwissProt: Q9GLE5?Cow SwissProt: P08253?Human SwissProt: P33434?Mouse SwissProt: P33436?Rat Unigene: 513617?Human Unigene: 29564?Mouse Unigene: 6422?Rat
Synonyms:	72 kDa gelatinase Antibody 72 kDa type IV collagenase Antibody 72kD type IV collagenase Antibody CLG 4 Antibody CLG 4A Antibody CLG4 Antibody CLG4A Antibody Collagenase Type 4 alpha Antibody Collagenase type IV A Antibody EC 3.4.24.24 Antibody Gelatinase A Antibody Gelatinase alpha Antibody Gelatinase neutrophil Antibody Matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) Antibody Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase Antibody Matrix metalloproteinase 2 Antibody Matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IV collagenase) Antibody Matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) Antibody Matrix metalloproteinase II Antibody Matrix metalloproteinase-2 Antibody MMP 2 Antibody MMP II Antibody MMP-2 Antibody MMP2 Antibody MMP2_HUMAN Antibody MONA Antibody Neutrophil gelatinase Antibody PEX Antibody TBE 1 Antibody TBE-1 Antibody
Information:	Target information shown above is from the UniProt Consortium.