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Anti-E2F4 Antibody

品牌：Antibodies

货号：

规格：100µg

货期：

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Anti-E2F4 Antibody

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Name:	Anti-E2F4 Antibody See all E2F4 primary antibodies
Description:	Goat polyclonal antibody to E2F4.
Applications:	ELISA, WB
Reactivity:	Human, Porcine
Immunogen:	Synthetic peptide corresponding to Human E2F4 (internal region).
Sequence:	C-PKELSEIFDPTR
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 µg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
Tissue Specificity:	Found in all tissue examined including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Sequence Similarities:	Belongs to the E2F/DP family.
Post-Translational Modification:	Differentially phosphorylated in vivo.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 1874 Human Entrez Gene: 100522677 Pig Omim: 600659 Human SwissProt: Q16254 Human Unigene: 108371 Human
Synonyms:	E2F 4 Antibody E2F transcription factor 4 Antibody E2F transcription factor 4 p107/p130 binding Antibody E2F-4 Antibody E2F4 Antibody E2F4_HUMAN Antibody p107/p130 binding protein Antibody Transcription factor E2F 4 Antibody Transcription factor E2F4 Antibody
Information:	Target information shown above is from the UniProt Consortium.