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Anti-MAP2 Antibody

品牌：Antibodies

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规格：25µl

货期：

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Anti-MAP2 Antibody

商品详情参考文献相关资料

Name:	Anti-MAP2 Antibody See all MAP2 primary antibodies
Description:	Chicken polyclonal antibody to MAP2.
Applications:	WB, IF/ICC, IHC
Dilutions:	WB: 1:20,000. IF/ICC and IHC: 1:10,000-1:20,000.
Reactivity:	Human, Horse, Cow, Porcine, Chicken, Rat, Mouse
Immunogen:	Recombinant human projection domain sequence, amino acids 377-1505.
Host:	Chicken
Clonality:	Polyclonal
Isotype:	IgY
Conjugate:	Unconjugated
Concentration:	21.0 mg/ml
Purity:	IgY preparation.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.
Storage:	Store at 4°C.

Function:	The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
Post-Translational Modification:	Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly. Isoform 3/MAP2c is probably phosphorylated by PKA at Ser-319, Ser-350 and Ser-382 and by FYN at Tyr-67. The interaction with KNDC1 enhances MAP2 threonine phosphorylation (By similarity).
Cellular Location:	Cytoplasm > Cytoskeleton. Cell projection > Dendrite.
Database Links:	Entrez Gene: 4133?Human Entrez Gene: 17756?Mouse Entrez Gene: 25595?Rat Omim: 157130?Human SwissProt: P11137?Human SwissProt: P20357?Mouse SwissProt: P15146?Rat Unigene: 368281?Human Unigene: 256966?Mouse Unigene: 436793?Mouse Unigene: 10484?Rat Unigene: 136301?Rat Unigene: 230443?Rat
Synonyms:	DKFZp686I2148 Antibody MAP 2 Antibody MAP dendrite specific Antibody MAP-2 Antibody MAP2 Antibody MAP2A Antibody MAP2B Antibody MAP2C Antibody Microtubule associated protein 2 Antibody Microtubule-associated protein 2 Antibody MTAP2_HUMAN Antibody
Information:	Target information shown above is from the UniProt Consortium.