Anti-Complement component C1s (human, pro- and activated enzyme) ABS 002-09 ABS 002-09|产品详情|进口试剂采购网

您好，欢迎来到拜力生物网站！请登录注册

我的订单 | 联系我们 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA试剂盒、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口试剂、Quidel代理、Swant代理、PBL Assay Science代理

所在位置：首页 > 产品中心 > BioPorto > BioPorto产品

订购信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-Complement component C1s (human, pro- and activated enzyme) ABS 002-09

品牌：

货号：ABS 002-09

规格：200 µg

货期：

立即购买加入购物车

Anti-Complement component C1s (human, pro- and activated enzyme)

商品详情参考文献相关资料

Cat. No.: ABS 002-09
Product name: Anti-Complement component C1s (human, pro- and activated enzyme)
Description: Mouse monoclonal antibody
Specificity: ABS 002-09 is specific for C1s proenzyme and activated free C1s
Immunogen: C1s proenzyme purified from human plasma
Application: ELISA
Species reactivity (positive): Human
Species reactivity (negative): Not determined
Subclass: IgG1/k
Gene ID: 716
Clone number: 9
Epitope: Epitope differs from that of ABS 002-49
Content: Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification: Protein-A purified
Form: Liquid
Solvent: 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage: 4-8ºC without exposure to light. No precautions necessary during handling.
Target: C1s proenzyme is a 79.8 kDa glycoprotein produced primarily by hepatocytes but also by other cells. The proenzyme is produced as a single-chain polypeptide of 688 aa. Upon activation the peptide is cleaved between R437 and I438 giving the activated enzyme consisting of two disulfide-linked chains, A chain (52.2 kDa) and B chain (27.7 kDa). The Ca-dependent catalytic subunit of the C1 complex (C1q, C1r, C1s) comprises of two C1s and two C1r molecules and this serine protease tetramer is responsible for the initial steps in the classical complement pathway, cleavage of C4 and C2.

Application 1: ELISA

ABS 002-09 reacts in ELISA when tested with activated C1s enzyme directly coated onto the microtiter well or in sandwich ELISA in combination with a polyclonal antibody in coat.

Plasma shows distinct positivity stained with ABS 002-09.