订购货号产品名称及规格价格（￥） 16020 Cyanine7.5 NHS ester, 1 mg 1430.00 26020 Cyanine7.5 NHS ester, 5 mg 2730.00 46020 Cyanine7.5 NHS ester, 25 mg 5330.00 56020 Cyanine7.5 NHS ester, 50 mg 9035.00 66020 Cyanine7.5 NHS ester, 100 mg 15470.00

商品详情参考文献相关资料

Cyanine7.5 NHS ester

Cyanine7.5是一种近红外荧光染料，具有很长的发射光谱，是此类荧光衍生而来的活性胺产品。

近红外照射很容易穿透组织因此常应用于体内成像领域。

该产品可以用于标记含有氨基的小分子物质，比如蛋白和多肽，通过近红外光谱成像技术（NIR imaging）来示踪他们在有机体内的分布。

中心聚亚甲基基团的增强的稳定性使得量子产率较其母结构Cy7.5® NHS提高20%。

图片关键词

推荐手册

氨基分子的NHS酯标记

Cy® is a trademark of GE Healthcare.

General properties

Appearance:	green powder
Molecular weight:	782.41
Molecular formula:	C₄₉H₅₂ClN₃O₄
Solubility:	soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control:	NMR 1H (95%) and 13C, TLC, functional testing
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	Download

Spectral properties

Excitation maximum, nm:	788
Extinction coefficient at excitation maximum, Lmol-1cm-1:	223000
Emission maximum, nm:	808

Yang, H.; Mao, H.; Wan, Z.; Zhu, A.; Guo, M.; Li, Y.; Li, X.; Wan, J.; Yang, X.; Shuai, X. et al. Micelles assembled with carbocyanine dyes for theranostic near-infrared fluorescent cancer imaging and photothermal therapy. Biomaterials, 2013, 34(36), 9124-9133. doi: 10.1016/j.biomaterials.2013.08.022
Zhou, K.; Liu, H.; Zhang, S.; Huang, X.; Wang, Y.; Huang, G.; Sumer, B.D.; Gao, J. Multicolored pH-Tunable and Activatable Fluorescence Nanoplatform Responsive to Physiologic pH Stimuli. Journal of the American Chemical Society, 2012, 134(18), 7803-7811. doi: 10.1021/ja300176w

Duong, H.T.T.; Dong, Z.; Su, L; Boyer, C.; George, J.; Davis, T.P.; Wang, J. The Use of Nanoparticles to Deliver Nitric Oxide to Hepatic Stellate Cells for Treating Liver Fibrosis and Portal Hypertension.Small. doi: 10.1002/smll.201402870
Lin, Y.-A.; Cheetham, A.G.; Zhang, P.; Ou, Y.-C.; Li, Y.; Liu, G.; Hermida Merino, D.; Hamley, I.W.; Cui, H.Multi-Walled Nanotubes Formed by Catanionic Mixtures of Drug Amphiphiles. ACS Nano, 2014, 8(12), 12690-12700. doi: 10.1021/nn505688b
Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p
Lu, H.D.; Soranno, D.E.; Rodell, C.B.; Kim, I.L.; Burdick, J.A. Secondary Photocrosslinking of Injectable Shear-Thinning Dock-and-Lock Hydrogels. Advanced Healthcare Materials, 2013, 2(7), 1028-1036. doi: 10.1002/adhm.201200343