Time Bioscience is hybrid biotech company founded by Tom Shi, Ph.D. and Martha Hadeler, MBA. The company manufactures signaling transduction drug discovery systems. The company also provides custom protein manufacturing, animal model services, as well as drug/compound screening services.

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Time Biosciencehttp://www.shijichina.com/goodsid/fenleiyi/3438493_timebioscience/1.html

PROTEINS:

• Wnt Signaling ligands: 
  rmWnt3a, rhWnt3a, rmWnt5a, rhWnt5a, rhWnt7a/b, rhWnt10a/b

• Wnt signaling inhibitors: DKK1 and DKK2

• Wnt signaling receptors: FZDs and LRPs

• Other signaling pathway proteins 

BETA-CATENIN REPORTER CELL LINES(GFP and Luciferase): 

• Preosteoblast Wnt reporter cell line

• Fibroblast Wnt reporter cell line

• Epithelial Wnt reporter cell line

• Colorectal cancer Wnt reporter cell lines

• Cell lines containing other signaling pathway reporter systems

COMPOUND SCREENING KITS:

• DKK1-LRP6 kit (96 and 384 wells)

• DKK2-LRP6 kit (96 and 384 wells)

• Sclerostin-LRP6 kit (96 and 384 wells)